Posted on August 21, 2013 · Posted in Brain Injury

Researchers in Wisconsin have documented — for the first time — irregular brain activity within the first 24 hours following a concussion, as well as an increased level of brain activity weeks later. It all suggests that the brain may compensate for the injury during the recovery time.

The findings of the study, led by a scientist at the Medical College of Wisconsin in Milwaukee, were published in the September issue of the Journal of the International Neuropsychological Society.

Thomas Hammeke, professor of psychiatry and behavioral medicine at the Wisconsin med school, was the lead author.  Researchers at  the Cleveland Clinic; St. Mary’s Hospital in Enid, Okla.; the University of North Carolina; Franklin College in Franklin, Ind., and the Marshfield Clinic in Marshfield, Wis., co-authored the paper.

In an effort to study recovery from sports concussion, 12 concussed high school football athletes and 12 uninjured teammates were evaluated at 13 hours and again at seven weeks following concussive injury, according to a press release from the Medical College of Wisconsin.

“The concussed athletes showed the expected post-concussive symptoms, including decreased reaction time and lowered cognitive abilities,” the release said. “Imaging via fMRI (functional magnetic resonance imaging) showed decreased activity in select regions of the right hemisphere of the brain, which suggests the poor cognitive performance of concussion patients is related to that under-activation of attentional brain circuits.”

Seven weeks after their injury, the concussed athletes showed improvement of cognitive abilities and normal reaction time. However, imaging at that time showed the post-concussed athletes had more activation in the brain’s attentional circuits than did the control athletes.

“This hyperactivation may represent a compensatory brain response that mediates recovery,” Hammeke said in a statement. “This is the first study to demonstrate that reversal in activation patterns, and that reversal matches the progression of symptoms from the time of the injury through clinical recovery.”

“Deciding when a concussed player should return to the playing field is currently an inexact science,” Dr. Stephen Rao, director of the Schey Center for Cognitive Neuroimaging at the Cleveland Clinic and a senior author, said in a statement. “Measuring changes in brain activity during the acute recovery period can provide a scientific basis for making this critical decision.”


About the Author

Attorney Gordon S. Johnson, Jr.
Past Chair Traumatic Brain Injury Litigation Group, American Association of Justice :: 800-992-9447